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BIRC2 (Baculoviral IAP Repeat-Containing 2, API1, C-IAP1, CIAP1, HIAP-2, HIAP2, IAP2, MIHB, RNF48)

Cat no: B2049-90


Supplier: United States Biological
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Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. The two isoforms of c-IAP (c-IAP1 and c-IAP2) are structurally related to XIAP, containing 3 baculoviral IAP repeat (BIR) motifs that are essential and sufficient for the binding and inhibition of caspases
Catalogue number: B2049-90
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human BIRC2 (Baculoviral IAP Repeat-containing 2). Crossreactivity: c-IAP1 and c-IAP2. Species Sequence Homology: mouse

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