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Bloom Syndrome, exon 22 (BLM, BS, RECQ2, RECQL2)

Bloom Syndrome, exon 22 (BLM, BS, RECQ2, RECQL2)

Cat no: B2163-03A

Supplier: United States Biological
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The Bloom's syndrome gene, BLM, plays an important role in the maintenance of genomic stability in somatic cells. The BLM protein is a 1417 amino acid peptide with homology to the RecQ helicases, a subfamily of DexH-box-containing DNA and RNA helicases. Cellular Localization: Nuclear Applications: Suitable for use in Western Blot and Immunoprecipitation,. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: B2163-03A
Reactivities: Mouse
Hosts: Rabbit
Applications: Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in TBS containing 0.1% BSA and 0.09% sodium azide.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: Tripathi, et al. BLM helicase dependent and independent roles of 53BP1 during replication st..J. Cell Biol. 178:9, 2007.
Additional info: Reacts with BLM Species Crossreactivity: This antibody reacts with Homo sapiens. Other species have not been tested. Mismatches: Mouse-3 (2 conserved, 1 not conserved).

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