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BLT1 Receptor Monoclonal Antibody (Clone 7B1)

Cat no: 120111

BLT1 Receptor Monoclonal Antibody (Clone 7B1)

Antigen: HeLa cells transfected with human BLT1 . Host: mouse, clone 7B1 . Cross-Reactivity: (+) human BLT1 receptor; (-) BLT2, CysLT1, and CysLT2 receptors . Application(s): FC,ICC, and IHC of frozen sections . The human BLT1 receptor is a GPCR that mediates the proinflammatory effects of leukotriene B4 (LTB4). Northern blotting reveals that the BLT1 receptor is highly expressed in leukocytes, U937 cells, and to a much lower extent in spleen and thymus.

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SPECIFICATIONS

Catalog Number

120111

Applications

ICC, IHC

Hosts

Mouse

Form

1 ea

P Type

Antibodies|Leukotrienes|Eicosanoids

Weight

0

Antigen

HeLa cells transfected with human BLT1

Storage Temp

-20

Shipping Temp

-20

Additional Info

The human BLT1 receptor is a G protein-coupled receptor that mediates the proinflammatory effects of leukotriene B4 (LTB4). Northern blotting reveals that the BLT1 receptor is highly expressed in leukocytes, U937 cells, and to a much lower extent in spleen and thymus. Sheep lung membranes have also been identified as a rich source for receptor isolation and purification. A second, low-affinity LTB4 receptor, BLT2, has also been cloned and characterized. Cayman Chemical's BLT1 Receptor Monoclonal Antibody is a useful tool for the detection of human BLT1 by flow cytometry, immunohistochemistry, and immunocytochemistry. The antibody does not cross react with the other leukotriene receptors (BLT2, CysLT1, or CysLT2) and does not work for Western blot analysis of BLT1.

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