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Products BRD3 bromodomain 2 TR-FRET Assay Kit
| Catalogue number: | 600640 |
| Weight: | 0 |
| Form: | 384 Well |
| P type: | Assay Kits |
| Shipping temp: | -80 |
| Storage temp: | -80 |
| Additional info: | Bromodomains recognize acetylated lysine residues and recruit regulatory complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. The isolated individual or tandem bromodomains of many BET family members, including BRD2, BRD3, BRD4, and BRDT, have been shown to bind acetylated histone tails, serving to couple histone acetylation marks to the transcriptional regulation of target promoters. Small molecule inhibitors of bromodomain interactions hold promise as useful therapeutics for human disease. Cayman's BRD3 bromodomain 2 TR-FRET Assay Kit is a homogeneous, TR-FRET assay method amenable to rapid characterization of inhibitors of bromodomain/acetylated peptide interaction in a high throughput format. This screening assay kit is robust, displaying a Z' >0.6. |
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