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BRD4/HUNK1 Polyclonal Antibody

Cat no: 13497

BRD4/HUNK1 Polyclonal Antibody

Antigen: synthetic peptide from human Brd4 within the region of amino acids 150-200 . Host: rabbit . Cross Reactivity:(+) chimpanzee, human, mouse, and rat BRD4 . Application(s): WB . BRD4 is a chromatin-binding protein whose expression is induced in response to growth stimuli. It acts at different stages of the cell cycle to regulate cell growth and chromosomal dynamics during mitosis.

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SPECIFICATIONS

Catalog Number

13497

Applications

WB

Hosts

Rabbit

Form

1 ea

P Type

Antibodies

Weight

0

Antigen

synthetic peptide from human Brd4 within the region of amino acids 150-200

Storage Temp

-20

Shipping Temp

-20

Additional Info

BRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of the BET protein family. It is a human homolog of mouse mCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms; the longer variant has a C-terminal region with proline and glutamine-rich domains. BRD4 is a chromatin-binding protein whos expression is induced in response to growth stimuli. BRD4 acts at different stages of the cell cycle by interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus.

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