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cAMP (Cyclic Adenosine Monophosphate, Cyclic AMP)

Cat no: B2671-01G

cAMP (Cyclic Adenosine Monophosphate, Cyclic AMP)

Cyclic adenosine monophosphate or cAMP is an intracellular by-product of ATP by adenylene cyclase when G-protein Coupled Receptors (GPCR) bind various ligands on the cell surface. Cyclic AMP acts as a second messenger for signal transduction across the cell membrane and is a part of kinase activation. It regulates the effects of glucagon and adrenaline along with the movement of calcium ions through ion channels. Since it is affected directly by GPCR activation, cAMP is studied as a means to monitor GPCR in the discovery of therapeutic drugs.\n\nApplications: \nSuitable for use in Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry (Paraffin): 1:100\nOptimal dilutions to be determined by the researcher.\n\nPositive Control:\nRat hippocampus and cerebellum tissue\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

B2671-01G

Size

50ul

Applications

IHC

Hosts

Rabbit

Reactivities

Rat

Form

Supplied as a liquid in PBS. Preservative free.

P Type

Pab

Purity

Serum

Additional Info

Recognizes rat cAMP.

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