Home  >  Products  >  CASP7 (Caspase-7, CASP-7, ICE-like Apoptotic Protease 3, ICE-LAP3, Apoptotic Protease Mch-3, CMH-1, Caspase-7 Subunit p20, Caspase-7 Subunit p11, MCH3, CASP7)
CASP7 (Caspase-7, CASP-7, ICE-like Apoptotic Protease 3, ICE-LAP3, Apoptotic Protease Mch-3, CMH-1, Caspase-7 Subunit p20, Caspase-7 Subunit p11, MCH3, CASP7)

CASP7 (Caspase-7, CASP-7, ICE-like Apoptotic Protease 3, ICE-LAP3, Apoptotic Protease Mch-3, CMH-1, Caspase-7 Subunit p20, Caspase-7 Subunit p11, MCH3, CASP7)

Cat no: C2087-29D9

Supplier: United States Biological
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Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase-9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1-2ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2087-29D9
Reactivities: Human
Hosts: Mouse
Applications: Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
Additional info: Recognizes human CASP7.

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