Supplier:
Cayman Chemical CompanyCat no: 13916
Caspase-14 Monoclonal Antibody (Clone 70A1426)
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SPECIFICATIONS
Catalog Number
13916
Applications
FC, WB
Hosts
Mouse
Form
1 ea
P Type
Antibodies|Intracellular Signaling
Weight
0
Antigen
synthetic peptide corresponding to mouse caspase-14 amino acids 2-18
Storage Temp
-20
Shipping Temp
-20
Additional Info
Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation, and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into an a2b2 tetramer to form the active enzyme. Caspase-14 has a conserved active site pentapeptide, QACRG. However, no proteolytic or biological activities have been identified so far. Its high expression in embryonic tissues and limited expression in adult tissues suggests that it may have some role during ontogenesis.
Applications
ELISA, IF, IP, WB
Hosts
Rabbit
Applications
ELISA, IP, WB
Hosts
Rabbit
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