Supplier:
Cayman Chemical CompanyCat no: 10009135
Caspase-3 Fluorescence Assay Kit
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SPECIFICATIONS
Catalog Number
10009135
Form
1 ea
P Type
Assay Kits
Weight
0
Storage Temp
-80
Shipping Temp
-80
Additional Info
Caspase-3 plays a central role in the execution of apoptosis. Activation of caspase-3 is commonly used as a biomarker for assessment of apoptosis and for understanding mechanisms of apoptosis induction. Cayman's caspase-3 fluorescence assay kit employs a specific caspase-3 substrate, N-Ac-DEVD-N'-MC-R110, which upon cleavage by active caspase-3, generates a highly fluorescent product that can be measured using excitation and emission wavelengths of 485 and 535 nm, respectively. The kit is simple to use and can be easily adapted to high throughput screening for therapeutic compounds that may regulate activation of caspase-3. Active caspase-3 is included in the kit as a positive control or as a quantitative standard. The caspase-3 inhibitor, N-Ac-Asp-Glu-Val-Asp-CHO, is also included in the kit for verifying the specificity of the substrate.
Applications
ELISA, IF, IP, WB
Hosts
Rabbit
Applications
ELISA, IP, WB
Hosts
Rabbit
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