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Caspase 4 Inhibitor, In Vivo, 10mM, Z-LEVD-FMK

Cat no: C2087-24C

Caspase 4 Inhibitor, In Vivo, 10mM, Z-LEVD-FMK

A synthetic peptide inhibitor that inhibits caspase-4 and related caspase activity. FMK inhibitors are irreversible and non-toxic. They can be used in both in vivo and in vitro studies.\n\nReady-to-use caspase inhibitors that are synthesized using a patent-protected method. These inhibitors are cell-permeable and nontoxic.\n\nCaspase Inhibitor Sets in the ready-to-use format are also available, providing researchers with more convenient tools for studying multiple apoptosis-inhibiting processes.\n\nSequence: Z-Leu-Glu-Val-Asp-FMK (FMK, fluoromethyl ketone)\n\nPurity: (same/more than) 95% by HPLC analysis\n\nConcentration: 2mM\n\nRecommended Usage:\nCell cultures (in vitro): the 10mM caspase inhibitors can be used at 1000X dilutions (e.g., Add 1ul to 1ml of culture medium).\nFor in vivo injections: 10mM caspase inhibitors are provided.\n\nStorage and Stability:\nLyophilized powder may be stored at 4 degrees C for short-term only. Reconstitute to nominal volume by adding sterile buffer. Aliquot and store at -20 degrees C. Reconstituted product is stable for 12 months at \n-20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

C2087-24C

Size

20ul

References

1. Thornberry, N.A., et al., J. Biol. Chem. 272: 17907-17911 (1997).

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