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CD137, Recombinant, Mouse:Fc (4-1BB, TNFRSF9)

Cat no: 044647

CD137, Recombinant, Mouse:Fc (4-1BB, TNFRSF9)

CD137 (4-1BB) is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice.\n\nSequence:\nThe extracellular domain of mouse CD137 (aa 1-185) is fused at the C-terminus to the Fc portion of human IgG1.\n\nStorage and Stability:\nShort-term Storage: +4 degrees C\nLong-term Storage: -20 degrees C\nWorking aliquots are stable for up to 3 months when stored at -20 degrees C.

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SPECIFICATIONS

Catalog Number

044647

Size

50ug

Form

0.2um filtered solution in PBS.

Purity

>95% (SDS-PAGE)

Alternative Names

4-1BB, TNFRSF9

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