Catalogue number: | 10004804 |
Hosts: | Mouse |
Applications: | Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation |
Weight: | 0 |
Form: | 1 ea |
P type: | Antibodies |
Shipping temp: | 4 |
Storage temp: | 4 |
Additional info: | Revealing the molecular signals involved in B and T cell activation is critical to the future discovery of therapeutics that can augment cell-mediated immune responses to disease. CD150 is a type I transmembrane glycoprotein that is involved in signal transduction of antigen specific responses in B and T cells. It is expressed by activated B cells isolated from tonsils and peripheral blood, B cells in germinal centers and mantle zone of lymph nodes, immature thymocytes, and CD45RO+CD45RA- subpopulation of T cells. This antibody has been used to detect CD150 in neoplastic cells from diffuse large B-cell lymphoma, Hodgkin's disease, hairy cell leukemia, and some tumors of ectodermal origin. |