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CD2 (E Rosette Receptor, T11, Lymphocyte Function Antigen 2, LFA-2, Sheep Erythrocyte Receptor)

Cat no: C2253-30

CD2 (E Rosette Receptor, T11, Lymphocyte Function Antigen 2, LFA-2, Sheep Erythrocyte Receptor)

CD2 antigen is expressed on about 70-80% of peripheral blood lymphocytes, 80-90% of thymocytes and NK cells. The primary ligand for CD2 is CD58 (LFA-3). The studies in previous and recent have revealed that CD48, CD59 and CD15 also act as ligands for CD2. CD2 antigen plays a role in T cell signaling and in lymphocyte adhesion and is a alternative pathway of T cell activation. There are membrane form on cell surface and soluble form in serum in CD2 antigen.\n\nApplications: \nSuitable for use in indirect immunofluorescence staining of human cells for flow cytometric analysis using 1ug/10e6 cells and is tested for immunohistochemical staining of acetone-fixed frozen sections and formalin

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SPECIFICATIONS

Catalog Number

C2253-30

Size

100ug

Applications

FC, IF, IHC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG1

References

1. Schlossman, S., L. Bloumsell, W. Gilks, et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P?245?346-348 Oxford University Press, New York

Additional Info

Recognizes a 50kD type I single-chain transmembrane glycoprotein called LFA-2 (lymphocyte function associated antigen-2) or sheep red blood cell (SRBC) receptor.

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