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CD32 (Fcg Receptor II) (Biotin)

Cat no: C2384-01B

CD32 (Fcg Receptor II) (Biotin)

Streptavidin: RPE\n\nFusion Partners: Spleen cells from immunized BALB/c mice were fused with cells of the NS1 myeloma cell line.\n\nRecommended Negative Controls: Mouse IgG1 Negative Control: BIOTIN\n\nThe antigen mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets.\n\nApplications:\nFlow Cytometry: Neat\nOptimal working dilutions to be determined by researcher.\n\nFlow Cytometry: Use 10ul of the suggested working dilution to label 10e6 cells or 100ul whole blood.

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SPECIFICATIONS

Catalog Number

C2384-01B

Size

100ug

Applications

FC

Hosts

Mouse

Reactivities

Hum, Can, NHP

Conjugates

Biotin

Form

Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.

P Type

Mab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG1

References

1. Greenman, J. et al. (1991). Characterisation of a new monoclonal anti-Fc gamma RII antibody, AT10, and its incorporation into a bispecific F(ab')2 derivative for recruitment of cytotoxic effectors. Mol. Immunol. 28: 1243-1254.

Additional Info

3H1232 recognizes the human CD32 antigen, a 40kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII).\n\nClone 3H1232 blocks the binding of IgG to Fc gamma R11 (4). Species Crossreactivity: canine neutrophils (3), Rhesus monkey

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