

Supplier:
Cayman Chemical CompanyCat no: 10004597
CD45 Monoclonal Antibody (Clone BRA-55)
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SPECIFICATIONS
Catalog Number
10004597
Applications
FC, ICC, IHC, WB
Hosts
Mouse
Form
1 ea
P Type
Antibodies
Weight
0
Antigen
human CD45
Storage Temp
4
Shipping Temp
4
Additional Info
CD45 is a type I transmembrane glycoprotein, common leukocyte antigen. As a result of alternative splicing between exons 4, 5, and 6, which encode A, B, and C determinants respectively, CD45 is expressed as four isoforms: CD45RA (Mr = 220 kDa), CD45RB (Mr = 210 kDa), CD45RC (Mr = 200 kDa), and CD45RO (Mr = 180 kDa). The highest level of CD45 expression is observed on lymphocytes. Resting T cells and NK cells express CD45RA and CD45RB. Activated T cells, memory T cells, monocytes, granulocytes, and dendritic cells express CD45RO and CD45RC; however B cells only express CD45RA. CD45 monoclonal antibodies are widely used for differential diagnosis of lymphoid malignancies.
Applications
ELISA, IF, IP, WB
Hosts
Rabbit
Applications
ELISA, IP, WB
Hosts
Rabbit
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