Home  >  Products  >  CD75 (Beta-galactoside alpha-2,6-sialyltransferase 1, Alpha 2,6-ST 1, B-cell Antigen CD75, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6Gal I, ST6GalI, Sialyltransferase 1, ST6GAL1, SIAT1)

CD75 (Beta-galactoside alpha-2,6-sialyltransferase 1, Alpha 2,6-ST 1, B-cell Antigen CD75, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6Gal I, ST6GalI, Sialyltransferase 1, ST6GAL1, SIAT1)

Cat no: C2430-25F


Supplier: United States Biological
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CD75, a 46kD Type II transmembrane protein, is a novel member of Sialyltransferase family of proteins. It is expressed in multiple cell types and is localized within the golgi apparatus. It is expressed in 2 isoforms and regulates the sialylation of various cellular glycoproteins which inturn play a key role in functions including brain development, neuronal plasticity, homing of lymphocytes, B-cell maturation and activation, thymocyte selection and also as receptors for viruses, toxins and parasites. Patholgical significance of CD75 has also been implicated in certain tumors. Applications: Suitable for use in Immunofluorescence, Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2430-25F
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
P type: Mab
Isotype: IgM,k
Purity: Purified by ammonium sulfate precipitation.
Additional info: Recognizes human ST6GAL1. Does not react with rat.

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