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CD8

Cat no: 030063

CD8

CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.\n\nApplications:\nFlow cytometry: 1:200-1:400.\nELISA: Suggested dilution 1:10000.\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

030063

Size

100ul

Applications

ELISA, FC

Hosts

Mouse

Reactivities

Hum

Form

Purified antibody in PBS, 0.03% sodium azide.

P Type

Mab

Purity

Purified

Isotype

IgG1

References

1. Veillette, A. et al. 1988. Cell 55:301.

Additional Info

Human

Alternative Names

MAL; p32; Leu2; CD8A

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