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CD81 (TAPA-1, Target of anti-Proliferative Antibody-1) (FITC)

Cat no: C2433-12D

CD81 (TAPA-1, Target of anti-Proliferative Antibody-1) (FITC)

Fusion Partners: Spleen cells from immunized Armenian hamsters were fused with cells of the mouse PX3-Ag.8.653 myeloma cell line.\n\nRecommended Negative Controls: Hamster IgG Negative Control: FITC\n\nFlow Cytometry: Use 10ul of the suggested working dilution to label 10e6 cells in 100ul.

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SPECIFICATIONS

Catalog Number

C2433-12D

Size

100ug

Applications

FC

Reactivities

Mouse, Rat

Form

Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. Labeled with fluorescein isothiocyanate (FITC).

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG

References

1. Clark, K. et al. (2001). PGRL is a major CD81 - associated protein on lymphocytes and distingushes a new family of cell surface proteins. J. Immunol. 167: 5115 - 5121.

Additional Info

Recognizes mouse and rat CD81, a 26kD cell surface glycoprotein that is also known as TAPA-1.In rodents CD81 is expressed at much higher levels on resting B cells than on T cells, although increased expression on T cells is found following activation. 3H1702 induces homotypic aggregation of B cells and inhibits anti Ig and IL-4 induced proliferation. 3H1702 requires the presence of both extracellular loops of TAPA-1 for binding. Species Crossreactivity: Mouse, rat

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