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CD96 (CD96 Antigen, DKFZp667E2122, MGC22596, TACTILE, T cell-ctivated Increased Late Expression Protein, T-cell Surface Protein Tactile Precursor) (PE)

Cat no: C2442-50B

CD96 (CD96 Antigen, DKFZp667E2122, MGC22596, TACTILE, T cell-ctivated Increased Late Expression Protein, T-cell Surface Protein Tactile Precursor) (PE)

Mouse CD96 (also Tactile) is a 170-180kD member of the Ig-Superfamily. It is expressed on CD4+ and CD8+ T cells, natural killer (NK) cells, NKT cells, resting monocytes, and gb T cells. Mouse CD96 binds to CD155 and nectin-1, and likely participates in cell-to-cell adhesion. Mature mouse CD96 is a 581aa), type I transmembrane glycoprotein. It contains a 515aa extracellular region (aa22-536) that contains three Ig-like domains, plus a 45aa cytoplasmic region. The two N-terminal domains are V-type (aa24-244), while the distal domain is a C-type structure (aa250-355). Unlike human CD96, there is no splice variant in the second V-type domain. There is, however, a potential isoform that shows a single Cys substitution for aa437- 602. Over aa1-536, mouse CD96 shares 55% and 79% aa identity with human and rat CD96, respectively.\n\nApplications: \nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nHybridoma: \nMyeloma cells with B cells from Balb/c mice.\n\nStorage and Stability:\nMay be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4 degrees C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.

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SPECIFICATIONS

Catalog Number

C2442-50B

Size

100Tests

Applications

FC

Hosts

Rat

Reactivities

Mouse

Form

Supplied as a liquid in PBS, 0.5% BSA and 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG2a

Additional Info

Recognizes mouse CD96.

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