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Cellular Apoptosis Susceptibility (Exportin-2, Exp2, Importin-alpha Re-exporter, Chromosome Segregation 1-like Protein, Cellular Apoptosis Susceptibility Protein, CSE1L, CAS, XPO2)

Cat no: C8049-88H


Supplier: United States Biological
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CAS (cellular apoptosis susceptibility) contains 971aa with 59% overall sequence homology as compared to yeast chromosome segregation homolog, CSE1. CAS is highly expressed in testis and fetal liver. CAS expression in human fibroblasts increases as cells are induced to proliferate and decreases in growth arrested cells. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-2ug/ml for 2h at RT Immunohistochemistry: 1:100 for 10min at RT Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10min followed by cooling at RT for 20min Optimal dilutions to be determined by the researcher. Positive Control: HeLa an NIH/3T3 cells Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C8049-88H
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human CAS. Species Crossreactivity: mouse and rat.

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