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Cellular Apoptosis Susceptibility (Exportin-2, Exp2, Importin-alpha Re-exporter, Chromosome Segregation 1-like Protein, Cellular Apoptosis Susceptibility Protein, CSE1L, CAS, XPO2)

Cat no: C8049-88H

Cellular Apoptosis Susceptibility (Exportin-2, Exp2, Importin-alpha Re-exporter, Chromosome Segregation 1-like Protein, Cellular Apoptosis Susceptibility Protein, CSE1L, CAS, XPO2)

CAS (cellular apoptosis susceptibility) contains 971aa with 59% overall sequence homology as compared to yeast chromosome segregation homolog, CSE1. CAS is highly expressed in testis and fetal liver. CAS expression in human fibroblasts increases as cells are induced to proliferate and decreases in growth arrested cells.\n\nApplications:\nSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 0.5-2ug/ml for 2h at RT\nImmunohistochemistry: 1:100 for 10min at RT\nStaining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10min followed by cooling at RT for 20min\nOptimal dilutions to be determined by the researcher.\n\nPositive Control:\nHeLa an NIH/3T3 cells\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

C8049-88H

Size

50ug

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Additional Info

Recognizes human CAS. Species Crossreactivity: mouse and rat.

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