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Products Clusterin (human) EIA Kit
| Catalogue number: | 580110 |
| Weight: | 0 |
| Form: | 1 ea |
| P type: | Assay Kits |
| Shipping temp: | 4 |
| Storage temp: | 4 |
| Additional info: | Clusterin is known by many names, including apolipoprotein J (Apo-J), Up-regulated in Alzheimer's disease brain (pADHC-9), Ku70-binding protein 1 (KUB-1), sulfated glycoprotein 2 (SGP-2), aging-associated gene 4 protein (AAG4), complement lysis inhibitor (CLI), and testosterone-repressed prostate message 2 (TRPM-2). In its major form, clusterin is a secreted disulfide-linked heterodimeric glycoprotein. Clusterin is very broadly expressed in essentially all tissues in mammals and is readily measured in cells, tissues, plasma, serum, semen, and tissue culture media. The expression of clusterin is up-regulated in developmental remodeling, apoptotic disease states such as neurodegeneration, and in response to injury and other stresses. Clusterin inhibits apoptosis, which appears to be one of many roles it plays in carcinogenesis. Variants in the clusterin gene are associated with the risk of developing Alzheimer's Disease. Cayman's Clusterin (human) EIA Kit is a competitive assay which can be used to measure Clusterin in human plasma, serum, or cell culture supernatants. |
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