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CORO1C (Coronin 3, Coronin-1C, Coronin-3, hCRNN4, CRNN4)

CORO1C (Coronin 3, Coronin-1C, Coronin-3, hCRNN4, CRNN4)

Cat no: C7901-38C

Supplier: United States Biological
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Coronin 3 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40aa typically bracketed by gly-his and trp-asp (GH-WD). These may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. By similarity, Coronin 3 may be involved in cytokinesis, motility, and signal transduction. Coronin 3 is ubiquitously expressed in all human tissues, in contrast to other known coronin-like molecules, each of which is expressed in a tissue-specific manner. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: >1:64,000 Western Blot: 0.2-1ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human lung or placenta Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C7901-38C
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Iizaka M, Han HJ, Akashi H, Furukawa Y, Nakajima Y, Sugano S, Ogawa M, Nakamura Y. Isolation and chromosomal assignment of a novel human gene, CORO1C, homologous to coronin-like actin-binding proteins. Cytogenet Cell Genet. 2000;88(3-4):221-4. PMID: 10828594.
Additional info: Recognizes human Coronin 3.

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