Catalogue number: | 160111 |
Hosts: | Mouse |
Applications: | Flow Cytometry, Immunofluorescence |
Weight: | 0 |
Form: | 250 microg |
Antigen: | purified ovine COX-1 |
P type: | Antibodies|Cyclooxygenase|Eicosanoids |
Isotype: | IgG2b |
Shipping temp: | 4 |
Storage temp: | 4 |
Additional info: | This product is derived by labeling the COX-1 monoclonal antibody (Item No. 160110) with fluorescein. COX-1 catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins: the conversion of arachidonic acid to prostaglandin H2. COX-1 is constitutively expressed in almost all animal tissues and is involved in the homeostatic role of eicosanoids. COX-1 is a 70 kDa protein which has been cloned from a variety of species including human, mouse, rat, and sheep. COX-1 from these species are approximately 90% identical at the amino acid level, whereas the homology between COX-1 and COX-2 is only about 60%. |