Catalogue number: | 160107 |
Hosts: | Rabbit |
Applications: | Western Blot |
Weight: | 0 |
Form: | 1 ea |
Antigen: | human COX-2 amino acids 567-599 (SVPDPELIKTVTINASSSRSGLDDINPTVLLKE){6556,2} |
P type: | Antibodies|Cyclooxygenase |
Shipping temp: | -20 |
Storage temp: | -20 |
Additional info: | COX-2 has been cloned from a variety of species including human, rat, and sheep and has a molecular weight of 72 kDa., COX-2 from these species are approximately 90% identical at the amino acid level, whereas the homology between COX-1 and COX-2 is only about 60%. Expression of COX-2 is regulated by growth factors, tumor promoters, bacterial endotoxin and cytokines, including IL-1.beta.. COX-2 is present in human breast tumors but is not expressed in normal breast tissue. |