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COX-2 (human) Polyclonal Antibody

Cat no: 160107

COX-2 (human) Polyclonal Antibody

Antigen: human COX-2 amino acids 567-599 . Host: rabbit . Cross-Reactivity: (+) human, mouse, and ovine COX-2; (-) COX-1 (all species) . Application(s): WB . Expression of COX-2, the inducible form of COX, is regulated by growth factor tumors, tumor promoters, bacterial endotoxin, and cytokines

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SPECIFICATIONS

Catalog Number

160107

Applications

WB

Hosts

Rabbit

Form

1 ea

P Type

Antibodies|Cyclooxygenase

Weight

0

Antigen

human COX-2 amino acids 567-599 (SVPDPELIKTVTINASSSRSGLDDINPTVLLKE){6556,2}

Storage Temp

-20

Shipping Temp

-20

Additional Info

COX-2 has been cloned from a variety of species including human, rat, and sheep and has a molecular weight of 72 kDa., COX-2 from these species are approximately 90% identical at the amino acid level, whereas the homology between COX-1 and COX-2 is only about 60%. Expression of COX-2 is regulated by growth factors, tumor promoters, bacterial endotoxin and cytokines, including IL-1.beta.. COX-2 is present in human breast tumors but is not expressed in normal breast tissue.

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