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Products COX-2 (mouse) Polyclonal FITC Antibody
| Catalogue number: | 10010096 |
| Hosts: | Rabbit |
| Applications: | Flow Cytometry, Immunofluorescence, Western Blot |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | mouse COX-2 amino acids 570-598 (DPQPTKTATINASASHSRLDDINPTVLIK){1982} |
| P type: | Antibodies |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | The primary use of this antibody conjugate is for the detection of cyclooxygenase 2 (COX-2) in mouse samples by direct immunolabeling. COX catalyze the first step in the biosynthesis of prostaglandins (PGs), thromboxanes, and prostacyclins: the conversion of arachidonic acid to PGH2. Discoveries of the induction of COX by a variety of stimuli such as phorbol esters, lipopolysaccharides, and cytokines led to the hypothosis that the inducible form of COX, COX-2, is responsible for the biosynthesis of PGs under acute inflammatory conditions. COX-2 is a 72 kDa protein which has been cloned from a variety of species including human, mouse, rat, and sheep. |
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