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CpG-A DNA, ODN 2216 Prototype, BioGenomics(TM)

Cat no: C7905-80


Supplier: United States Biological
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ODN 2216 is a prototype of the class of CpG-A oligodeoxynucleotides (ODN), also known as
Catalogue number: C7905-80
Applications: ELISA
Size: 200nmol
Form: Supplied as a lyophilized powder. Endotoxin levels are undetectable. Reconstitute with sterile ddH2O.
Purity: Purified
References: 1. Krieg, A; CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 2002, 20: 709. 2. Vollmer, J et al; Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities. Eur J Immunol 2004, 34: 251. 3. Kerkmann, M et al; Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells. J Immunol 2003, 170: 4465. 4. Krug, A et al; CpG-A oligonucleotides induce a monocyte-derived dendritic cell-like phenotype that preferentially activates CD8 T cells. J Immunol 2003, 170: 3468.

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