Dectin 2 (CLEC6A, CLECSF10, NKCL)

Dectin-2, also known as CLEC6A, is a type II transmembrane protein belonging to the C-Type lectin superfamily that is expressed on dendritic cells, Langerhans cells, monocytes, B cells, and activated T cells. Dectin-2 contains one carbohydrate recognition domain (CRD). Within the extracellular domain, human Dectin-2 shares 71% amino acid sequence identity with mouse Dectin-2a isoform. \n\nApplications:\nSuitable for use in ELISA and Flow Cytometry. Other applications not tested.\n\nRecommended Dilutions:\nFlow Cytometry: 2.5ug/10e6 cells using human blood-derived Optimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

D1876-49

Size

100ug

Applications

ELISA, FC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG1

Additional Info

Recognizes human Dectin 2. In Direct ELISA, no crossreactivity with recombinant mouse Dectin-2 alpha, recombinant human CLEC9A, recombinant human CLEC4D or recombinant human DLEC.