Home  >  Products  >  DERL3, NT (Degradation in Endoplasmic Reticulum Protein 3, DERtrin-3, Der1-like Protein 3, C22orf14, DER3, LLN2, Derlin-3)
DERL3, NT (Degradation in Endoplasmic Reticulum Protein 3, DERtrin-3, Der1-like Protein 3, C22orf14, DER3, LLN2, Derlin-3)

DERL3, NT (Degradation in Endoplasmic Reticulum Protein 3, DERtrin-3, Der1-like Protein 3, C22orf14, DER3, LLN2, Derlin-3)

Cat no: D3206-98M

Supplier: United States Biological
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Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1ug/ml Western Blot: 1ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D3206-98M
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, 0.01% sodium azide, 50% glycerol.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human DERL3.

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