Home  >  Products  >  Desmoglein 2 (Desmoglein-2, DSG2, ARVC10, ARVD10, Cadherin Family Member 5, CDHF5, CMD1BB, HDGC, MGC117034, MGC117036, MGC117037)
Desmoglein 2 (Desmoglein-2, DSG2, ARVC10, ARVD10, Cadherin Family Member 5, CDHF5, CMD1BB, HDGC, MGC117034, MGC117036, MGC117037)

Desmoglein 2 (Desmoglein-2, DSG2, ARVC10, ARVD10, Cadherin Family Member 5, CDHF5, CMD1BB, HDGC, MGC117034, MGC117036, MGC117037)

Cat no: D3221-83E

Supplier: United States Biological
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Desmoglein 2 is a 165kD glycoprotein that is a core component of the desmosome cell-cell junction between epithelial cells. Desmoglein 2 is synthesized in the basal layers of the skin. Applications: Suitable for use in Immunohistochemistry, Immunoprecipitation and Western Blot. Other applications not tested. Recommended Dilutions: Immunohistochemistry: Frozen sections Western Blot: 1:100-1:1000. Detects a band of ~165kD in A-431 cell lysates. Optimal dilutions to be determined by the researcher. Immunohistochemistry Positive Control: Skin Hybridoma: NS1 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D3221-83E
Reactivities: Human
Hosts: Mouse
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 200ug
Form: Supplied as a liquid in PBS, 0.09% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified
References: 1. Wahl. J. et al. (2002) Hybrid. Hybridomics 21:37-44 2. Hemmoranta, H. et al. (2006) Stem Cells Dev. 15: 839-51. 3. Wang, H. et al. (2012) J Virol. Mar 28. [Epub ahead of print] 4. Gornowicz-Porowska, J. et al. (2011) Acta Dermatovenerol Croat. 19: 150-5. 5. Yamamoto, Y. et al. (2007) J Biol Chem. 282: 17866-76.
Additional info: Recognizes human Desmoglein 2. Does not recognize Desmoglein 1 or Desmoglein 3.

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