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developmental pluripotency associated Protein 2 (DPPA-2, Pluripotent embryonic stem cell-related gene 1 protein, PESCRG1)

developmental pluripotency associated Protein 2 (DPPA-2, Pluripotent embryonic stem cell-related gene 1 protein, PESCRG1)

Cat no: D3221-94D

Supplier: United States Biological
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DPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen
Catalogue number: D3221-94D
Reactivities: Mouse
Hosts: Mouse
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
P type: Mab
Isotype: IgG2a,k
Purity: Purified by Protein G affinity chromatography.
Additional info: Recognizes mouse DPPA-2 at ~34kD.

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