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SPECIFICATIONS
Catalog Number
SMC-200D
Size
100ug
Applications
IHC, IP, WB
Hosts
Mouse
Reactivities
Hum, Mouse
Form
Protein G Purified
Clone
60B1220.1
Gene Id
1786
Isotype
IgG1 Kappa
Accession
NP_001370
Dilutions
2-4ug/mL (WB), 1-2ug/mL (IHC)
References
1. Bestor T., et al.(1988) J.Mol. Biol. 203: 971-983. 2. Yen R.W., Vertino P.M., Nelkin B.D. et al. (1992) Nucl.\nAcids Res. 20: 2287-2291.\n3. Xie S. et al. (1999) Gene 236: 87-95.\n4. Okano M., Bell D.W., Haber D.A. and Li E. (1999) Cell 99:\n247-257.\n5. Re
Swiss Prot
P26358
Storage Temp
-20
Concentration
0.5mg/mL
Research Area
Cell signaling, organelle marker
Shipping Temp
Blue Ice or 4
Storage Buffer
PBS, 0.05% BSA
Alternative Names
DNA Mtase, DNMT, MCMT, DNA methyltransferase 1
Scientific Background
Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic D
Certificate Of Analysis
2 ug/mL of SMC-200 was sufficient for detection of Dnmt1 in 10ug of mouse ES cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Applications
ELISA, IP, WB
Hosts
Mouse
Reactivities
Hum
Applications
ELISA, ICC, IHC
Hosts
Mouse
Reactivities
Hum, Mouse, Rat, Bov
Applications
ELISA, ICC, IHC
Hosts
Mouse
Reactivities
Hum, Mouse, Rat, Bov
Applications
ELISA, ICC, IHC, WB
Hosts
Mouse
Reactivities
Hum
Applications
ELISA, ICC, IHC, WB
Hosts
Mouse
Reactivities
Hum
Applications
ELISA, ICC, IHC, WB
Hosts
Mouse
Reactivities
Hum, Mouse, Rat, Bov, Can, Ch/Bird, GP, Ham, Prc, Rabbit, Sheep
Applications
ELISA, ICC, IHC, WB
Hosts
Mouse
Reactivities
Hum, Mouse, Rat, Bov, Can, Ch/Bird, GP, Ham, Prc, Rabbit, Sheep
Hosts
Mouse
Reactivities
Hum, Mouse, Rat, Ch/Bird, GP, Prc
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