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Dopamine Transporter, CT (Sodium-dependent Dopamine Transporter, DA Transporter, DAT, DAT1, Solute Carrier Family 6 Member 3, SLC6A3)

Cat no: D9020-30C

Dopamine Transporter, CT (Sodium-dependent Dopamine Transporter, DA Transporter, DAT, DAT1, Solute Carrier Family 6 Member 3, SLC6A3)

The Dopamine Transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson

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SPECIFICATIONS

Catalog Number

D9020-30C

Size

100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in 1 mM HEPES, pH 7.5, 150mM sodium chloride, 100ug per ml BSA, 50% glycerol.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

1. Kish SJ, Kalasinsky KS, Derkach P, Schmunk GA, Guttman M, Ang L, Adams V, Furukawa Y, Haycock JW (2001)Striatal dopaminergic and serotonergic markers in human heroin users. Neuropsychopharmacology 24:561-567. 2. Wilson JM, Kalasinsky KS, Levey AI, Bergeron C, Reiber G, Anthony RM, Schmunk GA, Shannak K, HaycockJW, Kish SJ (1996) Striatal dopamine nerve terminal markers in human, chronic methamphetamine users. NatMed 2:699-703. 3. Zhu MY, Klimek V, Haycock JW, Ordway GA (2000) Quantitation of tyrosine hydroxylase protein in the locuscoeruleus from postmortem human brain. J Neurosci Meth 99:37-44. 4. Zhu MY, Klimek V, Dilley GE, Haycock JW, Stockmeier C, Overholser JC, Meltzer HY, Ordway GA (1999)Elevated levels of tyrosine hydroxylase in the locus coeruleus in major depression. Biol Psychiatry 46:1275-1286.

Additional Info

Recognizes human Dopamine Transporter, C-Terminus.

Alternative Names

Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3

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