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Dopamine Transporter, CT (Sodium-dependent Dopamine Transporter, DA Transporter, DAT, DAT1, Solute Carrier Family 6 Member 3, SLC6A3)

Cat no: D9020-30C


Supplier: United States Biological
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The Dopamine Transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson
Catalogue number: D9020-30C
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ul
Form: Supplied as a liquid in 1 mM HEPES, pH 7.5, 150mM sodium chloride, 100ug per ml BSA, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3
References: 1. Kish SJ, Kalasinsky KS, Derkach P, Schmunk GA, Guttman M, Ang L, Adams V, Furukawa Y, Haycock JW (2001)Striatal dopaminergic and serotonergic markers in human heroin users. Neuropsychopharmacology 24:561-567. 2. Wilson JM, Kalasinsky KS, Levey AI, Bergeron C, Reiber G, Anthony RM, Schmunk GA, Shannak K, HaycockJW, Kish SJ (1996) Striatal dopamine nerve terminal markers in human, chronic methamphetamine users. NatMed 2:699-703. 3. Zhu MY, Klimek V, Haycock JW, Ordway GA (2000) Quantitation of tyrosine hydroxylase protein in the locuscoeruleus from postmortem human brain. J Neurosci Meth 99:37-44. 4. Zhu MY, Klimek V, Dilley GE, Haycock JW, Stockmeier C, Overholser JC, Meltzer HY, Ordway GA (1999)Elevated levels of tyrosine hydroxylase in the locus coeruleus in major depression. Biol Psychiatry 46:1275-1286.
Additional info: Recognizes human Dopamine Transporter, C-Terminus.

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