E2F1 Transcription Factor (E2F 1, Retinoblastoma associated protein 1, Retinoblastoma binding protein 3, PBR3, RBAP-1, RBBP3, RBP3)

Cellular Localization: Nuclear\n\nApplications: \nSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

E0010-02G

Size

100ul

Applications

IP, WB

Hosts

Rabbit

Reactivities

Hum

Form

10mM PBS. [pH 7.4] with 1% BSA containing 15mM Sodium Azide

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

Cartwright P et al. E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription. Oncogene 17:611-23 (1998). <PUBMED:9704927>Rogers KT et al. DP-2, a heterodimeric partner of E2F: identification and characterization of DP-2 proteins expressed in vivo. Proc Natl Acad Sci U S A 93:7594-9 (1996). <PUBMED:8755520>Moberg K et al. E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry. Mol Cell Biol 16:1436-49 (1996). <PUBMED:8657117>Hateboer G et al. Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins. Genes Dev 10:2960-70 (1996). <PUBMED:8956997>

Additional Info

Species Crossreactivity: Crossreacts with Human.

Alternative Names

E2F 1, Retinoblastoma associated protein 1, Retinoblastoma binding protein 3, PBR3, RBAP-1, RBBP-3, RBBP3, RBP3