Eukaryotic initiation factor-2B (EIF2B) is a GTP exchange protein essential for protein synthesis. It consists of alpha (EIF2B1; 606686), beta (EIF2B2), y (EIF2B3; 606273), delta (EIF2B4; 606687), and epsilon (EIF2B5; 603945) subunits. EIF2B activates its EIF2 (see 603907) substrate by exchanging EIF2-bound GDP for GTP.
Source:
Recombinant protein corresponding to EIF2 B2, fused to T7 tag at N-terminal expressed in E.coli.
Molecular Weight:
~40.4kD
Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution:
Optimal dilutions to be determined by the researcher.
Storage and Stability:
Aliquot to avoid repeated freezing and thawing and store at -70 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.