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EIF4A2, CT (EIF4A2, DDX2B, EIF4F, Eukaryotic initiation factor 4A-II, ATP-dependent RNA helicase eIF4A-2) (AP)

Cat no: 035009-AP

EIF4A2, CT (EIF4A2, DDX2B, EIF4F, Eukaryotic initiation factor 4A-II, ATP-dependent RNA helicase eIF4A-2) (AP)

Eukaryotic initiation factor 4A plays an important role in the binding of mRNA to the 43S preinitiation complex when protein synthesis begins. Two highly homologous forms of functional EIF4A genes, Eif4a1 and Eif4a2, have been isolated in mice; yeast cells also possess 2 EIF4A genes, TIF1 and TIF2. The murine Eif4a and yeast TIF genes appear to belong to a DEAD-box gene family, whose members exhibit extensive amino acid similarity and contain the asp-glu-ala-asp (DEAD) sequence. DEAD-box genes have been identified in species ranging from E-coli to humans. Their function appears to be related to transcriptional/translational regulation (referenced from OMIM).\n\nApplications:\nSuitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\nImmunohistochemistry: 1:50-100\nFlow Cytometry: 1:10-50\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Do not freeze alkaline phosphatase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

035009-AP

Size

200ul

Applications

ELISA, FC, IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Alkaline Phosphatase.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Martins-de-Souza,D., et.al., J Neural Transm 116 (3), 275-289 (2009)\nLin,C.J., et.al., Cancer Res. 68 (13), 5326-5334 (2008)

Additional Info

Human

Alternative Names

EIF4A2, DDX2B, EIF4F, Eukaryotic initiation factor 4A-II, ATP-dependent RNA helicase eIF4A-2

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