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Endothelial Lipase Polyclonal Antibody

Cat no: 100030

Endothelial Lipase Polyclonal Antibody

Antigen: human endothelial lipase amino acids 19-32 . Host: rabbit . Cross Reactivity: (+) human, mouse, rat, porcine, and ovine endothelial lipase . Application(s): IHC and WB . EL is a major genetic determinant for the concentration, structure, and metabolism of HDL, which protects against atherosclerosis

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SPECIFICATIONS

Catalog Number

100030

Applications

IHC, WB

Hosts

Rabbit

Form

1 ea

P Type

Antibodies

Weight

0

Antigen

human endothelial lipase amino acids 19-32

Storage Temp

-20

Shipping Temp

-20

Additional Info

Endothelial lipase (EL) is a major genetic determinant for the concentration, structure, and metabolism of high-density lipoprotein, which protects against atherosclerosis. It was originally cloned from endothelial cells and found to be expressed in a distinct and complementary tissue-restricted fashion, with high-level expression in the liver, placenta, lung, ovary, and macrophage. Immunohistochemical studies demonstrate that EL is expressed in infiltrating cells such as macrophages within atheromatous plaques, in addition to endothelial and smooth muscle cells in non-atherosclerotic coronary arteries. Furthermore, EL expression is detected in the neovasculature within atheromatous plaques in atherosclerotic coronary arteries, indicating that EL may have unique functional roles in atherosclerosis. Cayman Chemical's EL polyclonal antibody can be used for western blot and immunohistochemical analysis for EL on samples of human, murine, rat, porcine, and ovine origin. Other applications for use of this antibody have not yet been tested.

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