EndoZyme® is intended for in vitro quantitative determination of endotoxin (lipopolysaccharide, LPS) in pharmaceuticals and biological substances as well as for medical device testing.
The endotoxin-specificity of EndoZyme® eliminates all false-positive and elevated results seen with LAL due to ß-glucan reactions in the LAL cascade. Adding the ease-of-use and excellent lot-to-lot consistency, EndoZyme® is a representative of modern recombinant methods, moving away from the animal source which for decades has been the horseshoe crab.
Having a homogeneous assay format without a solid phase, EndoZyme® is best suited for non-complex samples and buffer conditions. For complex sample matrices, EndoLISA® is recommended.