

Supplier:
Cayman Chemical CompanyCat no: 160880
eNOS Polyclonal Antiserum
Prices direct from Cayman Chemical Company
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Exclusive Biosave savings/discounts
SPECIFICATIONS
Catalog Number
160880
Applications
IP, WB
Hosts
Rabbit
Form
1 ea
P Type
Antibodies
Weight
0
Antigen
human eNOS amino acids 1186-1203 (RGAVPWAFDPPGSDTNSP){2667,3438,1902}
Storage Temp
-20
Shipping Temp
-20
Additional Info
eNOS catalyzes the formation of NO from L-arginine in many cell types including vascular endothelium, bronchiolar epithelium, cardiac myocytes, spleen, and kidney. Although eNOS was initially characterized as a constitutive enzyme, expression of eNOS mRNA is altered by many factors including shear stress, fibroblast growth factor, hypoxia, and LPS. eNOS is myristoylated and palmitoylated at the N-terminus, modifications which are required for localization to the plasmalalemmal caveolae of endothelial cells. Additionally, eNOS is phosphorylated on Ser1179 by protein kinase Akt resulting in an increase in NOS activity.
Applications
ELISA, IF, IP, WB
Hosts
Rabbit
Applications
ELISA, IP, WB
Hosts
Rabbit
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