Supplier:
Cayman Chemical CompanyCat no: 101740
EP1 Receptor Polyclonal Antibody
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SPECIFICATIONS
Catalog Number
101740
Applications
ICC, WB
Hosts
Rabbit
Form
1 ea
P Type
Antibodies|Eicosanoids
Weight
0
Antigen
human EP1 receptor C-terminal amino acids 380-402{3176}
Storage Temp
-20
Shipping Temp
-20
Additional Info
The biological effects of PGE2 are mediated through interaction with four distinct membrane-bound G-protein coupled EP receptors: EP1, EP2, EP3, and EP4. Binding of PGE2 to the EP1 receptor results in an increase in phosphatidyl inositol turnover with subsequent increase in intracellular free Ca2+. Pharmacologically, EP1 receptors mediate contraction of smooth muscle. The human EP1 receptor is comprised of 402 amino acids with a molecular mass of approximately 42,000. The EP1 receptor is expressed in a variety of tissues, including the kidney, lung, and sensory neuron. Within the kidney, the EP1 receptor is expressed at high levels in the cortical, outer medullary, and inner medullary collecting duct.
Applications
ELISA, IF, IP, WB
Hosts
Rabbit
Applications
ELISA, IP, WB
Hosts
Rabbit
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