Home  >  Products  >  ErbB4 (c-erbB4, HER4, MGC138404, p180erbB4, Proto-oncogene-like Protein c-ErbB-4, Receptor Tyrosine-protein Kinase erbB-4, Tyrosine Kinase-type Cell Surface Receptor HER4)

ErbB4 (c-erbB4, HER4, MGC138404, p180erbB4, Proto-oncogene-like Protein c-ErbB-4, Receptor Tyrosine-protein Kinase erbB-4, Tyrosine Kinase-type Cell Surface Receptor HER4)

Cat no: E3451-40N


Supplier: United States Biological
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ERBB-4 receptor tyrosine kinase is activated by neuregulins, nrg- 2, nrg-3, heparin-binding egf-like growth factor, betacellulin and ntak to regulate cell proliferation and differentiation. Several isoforms of the ERBB-4 receptor tyrosine kinase have been identified and differ functionally in their response to phorbol ester: they represent cleavable and noncleavable forms of the receptor. These isoforms are differentially expressed in tissues. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 60ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human glomerulus and renal tubular epithelium in cortex Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: E3451-40N
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in PBS, 0.1% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: EC=2.7.10.1, v-erb-a Erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian)
Additional info: Recognizes human ERBB-4.

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