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ERK2 (Extracellular Signal-regulated Kinase 2, ERK-2, ERK, ERT1, MAP Kinase Isoform p42, Mitogen-activated Protein Kinase 1, MAP Kinase 1, MAPK 1, MAPK1, Mitogen-activated Protein Kinase 2, MAP Kinase 2, MAPK 2, MAPK2, p41mapk, p42-MAPK, P42MAPK, PRKM1, P

Cat no: E3452-57U

ERK2 (Extracellular Signal-regulated Kinase 2, ERK-2, ERK, ERT1, MAP Kinase Isoform p42, Mitogen-activated Protein Kinase 1, MAP Kinase 1, MAPK 1, MAPK1, Mitogen-activated Protein Kinase 2, MAP Kinase 2, MAPK 2, MAPK2, p41mapk, p42-MAPK, P42MAPK, PRKM1, P

Both p44 and p42 MAP kinases (Erk1 and Erk2) function in a protein kinase cascade that plays a critical role in the regulation of cell growth and differentiation. Activation of MAP kinases occurs through phosphorylation of threonine and tyrosine (202 and 204 of human MAP kinase [Erk1] or 183 and 185 of rat Erk2) at the sequence TEY by a single upstream MAP kinase kinase (MEK). Both kinases are known to weakly autophosphorylate on tyrosine.\n\nApplications:\nSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 0.5-4ug/ml\nImmunohistochemistry: 10-20ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

E3452-57U

Size

100ug

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in PBS, 1% BSA, 0.02% thimerosal, 50% glycerol.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

Additional Info

Recognizes human Erk2. Species Crossreactivity: mouse and rat.

Read more on Supplier website

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

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