Everolimus

Cat no: 011892

Supplier: United States Biological

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Everolimus Macrolide immunosuppressant; Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Melting Point: As Reported Solubility: As Reported Method for Determining Identity: Proton NMR (CDCl3) Spectroscopic and Mass Spectrometric Analysis TLC Condtions: As Reported Elemental Analysis: As Reported Ethyl Acetate: 2% Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hygroscopic, Note: Inert atmosphere is preferred for long term storage. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards:

Catalogue number:	011892
Size:	10mg
Form:	As Reported
Purity:	~90%
Alternative names:	40-O-(2-Hydroxyethyl)rapamycin; 42-O-(2-Hydroxy)ethyl Rapamycin; Afinitor; Certican; RAD; RAD 001; SDZ-RAD; XIENCE V;
References:	1. Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001). 2. Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001). 3. Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002).

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Everolimus

Cat no: 011892

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