Exportin-1 (XPO1, Exp1, Chromosome Region Maintenance 1 Protein Homolog, CRM1)

Cat no: E9009-31B

Supplier: United States Biological

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Description
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XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1-3ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	E9009-31B
Reactivities:	Human
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	50ug
Form:	Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
P type:	Pab
Isotype:	IgG
Purity:	Purified by Protein G affinity chromatography.
Additional info:	Recognizes human XPO1. Species sequence homology: Bovine, chimpanzee, canine, mouse and rat.

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Exportin-1 (XPO1, Exp1, Chromosome Region Maintenance 1 Protein Homolog, CRM1)

Cat no: E9009-31B

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