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Exportin 5 (XPO5, FLJ14239, FLJ32057, FLJ45606, KIAA1291, Exportin-5, Ran-binding protein 21)

Cat no: 045586

Exportin 5 (XPO5, FLJ14239, FLJ32057, FLJ45606, KIAA1291, Exportin-5, Ran-binding protein 21)

Exportin 5 is a member of the karyopherin family that is required for the transport of small RNAs and double-stranded RNA-binding proteins from the nucleus to the cytoplasm. This protein translocates cargo through the nuclear pore complex in a RanGTP-dependent process (1). Exportin 5 is expressed in the heart, brain, placenta, lung, skeletal muscle, kidney, and pancreas (2).\n\nApplications: \nSuitable for use in Western Blot, and Immunocytochemistry. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1:1000-10,000\nImmunocytochemistry: 1:100-250\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. \n\nManufactured incorporating RabMAb(R) technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.

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SPECIFICATIONS

Catalog Number

045586

Size

100ul

Applications

ICC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in PBS, sodium azide, BSA, glycerol.

P Type

Mab

Purity

Supernatant

References

1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8. 2. The UniProt Consortium Reorganizing the protein space at the Universal Protein Resource (UniProt) Nucleic Acids Res. 40: D71-D75 (2012).

Additional Info

Recognizes human Exportin 5. Species sequence homology: Mouse, rat.

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