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Products FABP4 Polyclonal Antibody
| Catalogue number: | 10004944 |
| Hosts: | Rabbit |
| Applications: | Immunocytochemistry, Western Blot |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | human FABP4 amino acids 103-118 |
| P type: | Antibodies|Fatty Acids|PPAR |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | FABP4 is primarily expressed in adipocytes but is also expressed in activated macrophages, indicating that the protein plays a critical role in foam cell formation and thus atherosclerosis. FABP4 was first purified from mouse 3T3-L1 adipocytes and then from human adipocytes and was named ALBP. The expression of FABP4 is developmentally regulated by fatty acids, PPAR(gamma) agonists, and insulin. In mice, deficiency of FABP4 prevents the development of hyperinsulinemia and insulin resistance in genetic and diet-induced obesity. |
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