Supplier:
United States BiologicalCat no: F0018-65
Factor XIa, Human
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SPECIFICATIONS
Catalog Number
F0018-65
Size
50ug
Form
The factor XIa is supplied in 50% glycerol/H2O.
Purity
(same/more than)95% by SDS-PAGE. Factor XIa is prepared by activating purified factor XI with factor XIIa. Following activation, the mixture is passed over a column of immobilized anti-factor XII to remove the factor XIIa, and further purified on heparin-Sepharose. Purity is assessed by SDS PAGE analysis. Activity is determined in a clotting assay using factor XI deficient plasma.
References
1. Kurachi, K. and Davie, E.W., Biochemistry, 16, 5831 (1977).\n2. Bouma, B.N. and Griffen, J.H., J. Biol. Chem., 252, 6432 (1977).\n3. Kurachi, K., et al., Biochemistry, 19, 1330 (1980).\n4. Thompson, R.E., et al., J. Clin. Invest., 60, 1376 (1977).\n5. Scott, C.F., et al., J. Clin. Invest., 69, 844 (1982).\n6. Heck, L.W. and Kaplan, A.P., J. Exp. Med., 140, 1615 (1974).
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