Home  >  Products  >  FAK (Focal Adhesion Associated Protein Tyrosine Kinase, Focal Adhesion Kinase, FADK, Focal Adhesion Kinase 1, FADK 1, FAK1, BC3, FRNK, pp125FAK, Protein Tyrosine Kinase 2, PTK2)

FAK (Focal Adhesion Associated Protein Tyrosine Kinase, Focal Adhesion Kinase, FADK, Focal Adhesion Kinase 1, FADK 1, FAK1, BC3, FRNK, pp125FAK, Protein Tyrosine Kinase 2, PTK2)

Cat no: F0019-54C


Supplier: United States Biological
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FAK plays a potential role in oncogenic transformation, and its expression is thought to be correlated to tumor invasiveness. Applications: Suitable for use in Immunohistochemistry (paraffin). Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 2-5ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Ductal and lobular epithelium. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: F0019-54C
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.7, 0.09% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: EC=2.7.10.2
References: 1. McLean, G.W. et al. (2005) The role of focal-adhesion kinase in cancer - a new therapeutic opportunity. Nat. Rev. Cancer. 5: 505-515. 2. Mitra, S.K. et al. (2005) Focal adhesion kinase: in command and control of cell motility. Nat. Rev. Mol. Cell. 6: 56-58.
Additional info: Recognizes human focal adhesion kinase.

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