Fas Ligand (FASL)

Application(s): \nFlow Cytometry\nImmunohistochemistry (frozen sections, paraffin sections)\nFor Western blot, we recommend MAb to FasL (mouse), MAb to FasL (human).

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SPECIFICATIONS

Catalog Number

F0019-66J

Size

100ug

Applications

FC, IHC, WB

Hosts

Rat

Reactivities

Mouse

Form

Liquid. Purified antibody in PBS containing 0.02% sodium azide.\n

P Type

Mab

Purity

(same/more than)95% (by SDS-PAGE).

Isotype

IgM

References

1. Characterization of the non-functional Fas ligand of gld mice: M. Hahne, et al.; Int. Immunol. 7: 1381 (1995). 2. Peripheral T cells undergoing superantigen-induced apoptosis in vivo express B220 and upregulate Fas and Fas ligand: T. Renno, et al.; J. Exp. Med. 183: 431 (1996). 3. Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover: L.E. French, et al.; J. Cell. Biol. 133: 335 (1996). 4. Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape: M. Hahne, et al.; Science 274: 1363 (1996). 5. Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in the brain?: P. Saas, et al.; J. Clin. Invest. 99: 1173 (1997). 6. Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis: Y. Refaeli, et al.; Immunity 8: 615 (1998). 7. The regulation of CD95 ligand expression and function in CTL: J.H. Li, et al.; J. Immunol. 161: 3943 (1998). 8. Fas ligand overexpression on allograft endothelium inhibits inflammatory cell infiltration and transplant-associated intimal hyperplasia: M. Sata, et al.; J. Immunol. 166: 6964 (2001). 9. Vascular endothelial cells and smooth muscle cells differ in expression of Fas and Fas ligand and in sensitivity to Fas ligand-induced cell death: implications for vascular disease and therapy: M. Sata, et al.; Arterioscler. Thromb. Vasc. Biol. 20: 309 (2000).

Additional Info

Recognizes mouse FasL.