Fatty Acid Binding Protein 2 (Intestinal Fatty acid binding protein 2, mal1, MGC133132)

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15kD proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance.\n\nAlternate Names: anti-FABP2 antibody, anti-fatty acid binding protein 2, intestinal antibody, anti-FABPI antibody, anti-I-FABP antibody, anti-MGC133132 antibody, anti-Fatty acid-binding protein, intestinal antibody, anti-intestinal fatty acid binding protein 2 antibody \n\nEpitope: EGVEAKRIFKKD\n\nApplications: \nSuitable for use in ELISA, Western Blotting. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1:55,000-1:65,000\nWestern Blotting: 1:1000-1:2000\nOptimal dilutions to be determined by the researcher.\n\nPositive Control:Human Duodenum lysate \n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

F0019-86A

Size

100ug

Applications

ELISA, WB

Hosts

Goat

Reactivities

Hum

Form

Supplied as a liquid in tris-saline [pH7.3] with 0.5% BSA, 0.02% sodium azide.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

Takakura Y, Yoshioka K, Umekawa T, Kogure A, Toda H, Yoshikawa T, Yoshida T. Thr54 allele of the FABP2 gene affects resting metabolic rate and visceral obesity. Diabetes Res Clin Pract. 2005 Jan;67(1):36-42. PMID: 15620432

Additional Info

Recognizes human FABP2. Expected based upon sequence homology: canine, mouse