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Fatty Acid Binding Protein, Ileal (IL-FABP, FABP6)

Fatty Acid Binding Protein, Ileal (IL-FABP, FABP6)

Cat no: F0019-88

Supplier: United States Biological
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FABPs are small intracellular proteins (~13-14kD) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. IL-FABP is localized in the intestine, ovary, adrenals and stomach. Applications: Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry (Paraffin): 1:50 Western Blot: 1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F0019-88
Reactivities: Rat
Hosts: Rabbit
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein A affinity chromatography.
Alternative names: FABP6, gastrotropin, ileal lipid-binding protein, I-BABP
References: 1.Veerkamp, J et al; Cytoplasmic fatty acid-binding proteins: their structure and genes. Prog Lipid Res 1995, 34: 17 2.Veerkamp, J et al; Stuctural and functional studies on different human FABP types. Mol Cell Biochem 1999, 192: 137
Additional info: Recognizes mouse Ileal Fatty Acid Binding Protein of both natural and recombinant origin. Species Crossreactivity: rat.

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